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March 15, 2022 News by Steve Bryson, PhD

Antibodies to ERT Use Common in Children, Not Likely to Limit Efficacy

Most children with Pompe disease in a small study developed antibodies against the enzyme replacement therapy Myozyme (alglucosidase alfa) — marketed in the U.S. as Lumizyme — but their presence did not limit treatment efficacy, its researchers reported. Children with the highest levels of antibodies also experienced most of…

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